• Mia Astridivia Nursing Science, Faculty of Nursing, Universitas Indonesia, Depok, West Java, Indonesia
  • Kuntarti Department Basic of Science Health Nursing, Faculty of Nursing, Universitas Indonesia Depok, West Java, Indonesia



Berlin Questionnaire, Hypertension, Obstructive Sleep Apnea, Sleep


Over the past few years, the number hypertensive patients in Indonesia have increased rapidly. Previous studies have investigated that OSA independently is important risk factor of hypertension. In Indonesia, there were still lacks of study between OSA and blood pressure on population-based or clinical-population.The objective of this study was to know the relation of OSA to blood pressure on hypertensive patients. This study design was descriptive correlation with cross-sectional approach on 96 hypertensive patients  at one of the community health center in Depok city, who were selected with consecutive sampling technique. The OSA was assessed by using the Berlin questionnaire, blood pressure was assessed by aneroid sphygmomanometer, and anthropometric measurements was assessed by weight scale and stature meter. This study showed that 57,3% subjects had the high risk for OSA. The result of analysis by using the Mann-Whitney test showed that OSA related to systolic blood pressure (p= 0.028; CI95%= 0.000-0.066) but was not related to diastolic blood pressure (p= 0.231; CI95%=0.229-0.416),although there was difference of 10 mmHg, higher on hypertensive patient with high risk OSA. This study showed that OSA related to increasing morbidity of hypertension because its effect on elevated blood pressure.The assessment and management of OSA needs to be implemented in providing health care, in order to increase the quality of life for patients especially on hypertensive patients.


Agency for Health Research and Development. (2013). Riset kesehatan dasar. Accessed from

Division of Sleep Medicine at Harvard Medical School. (2011). The Apnea Hypopnea Index (AHI) and oxygen desaturation levels are used to indicate the severity of obstructive sleep apnea. Accessed from

Dudenbostel, T., & Calhoun, D. A. (2012). Resistant hypertension, obstructive sleep apnoea and aldosterone. Journal of Human Hypertension, 26(5),

Garvey, J. F., Pengo, M. F., Drakatos, P., & Kent, B. D. (2015). Epidemiological aspects of obstructive sleep apnea. Journal of Thoracic Diseases, 7(5), 920-929.

Iochimescu, Ocatavian, C. (2011). Contemporary sleep medicine for patients. UAE: Bentham Science Publishers.

Kashyap, R., Hock, L. M., & Bowman, T. J. (2001). Higher prevalence of smoking in patients diagnosed as having obstructive sleep apnea. Sleep Breath, 5(4),

Kim, J., Yi, H., Shin, K. R., Kim, J. H., Jung, K. H., & Shin, C. (2007). Snoring as an independent risk factor for hypertension in the nonobese population: the Korean Health and Genome Study. American Journal of Hypertension, 20(8), 819-824. doi:10.1016/j.amjhyper.2007.03.007

Kim, J.S., Song, W.H., Shin, C., Park, C.G., Seo, H.S., Shim, W.J., et al. (2001). The prevalence and awareness of hypertension and the relationship between hypertension and snoring in the Korean population. Korean Journal of Internal Medicine, 16,

Lin, C. M., Davidson, T. M., & Ancoli-Israel, S. (2008). Gender differences in obstructive sleep apnea and treatment implications. Sleep Medicine Review, 12(6)

Menon, A., & Kumar, M. (2013). Influence of body position on severity of obstructive sleep apnea: a systematic review. ISRN Otorangology. Vol 2013

Mohsenin, V. (2003). Effects of gender on upper airway collapsibility and severity of obstructive sleep apnea. Sleep Medicine, 4(6), 523-529

Ng, N., Weinehall, L., & Ohman, A. (2007). 'If I don't smoke, I'm not a real man'--Indonesian teenage boys' views about smoking. Health Education Research, 22(6), 794-804.

Pensuksan, W. C., Chen, X., Lohsoonthorn, V., Lertmaharit, S., Gelaye, B., & Williams, M. A. (2014). High risk for obstructive sleep apnea in relation to hypertension among southeast asian young adults: Role of obesity as an effect modifier. American Journal of Hypertension, 27(2), 229-236.

Priou, P., Vaillant, M. L., Meslier, N., Paris, A., Pigeanne, T., Nguyen, X., et al. (2014). Cumulative association of obstructive sleep apnea severity and short sleep duration with the risk for hypertension. PLoS ONE, 9(12)

Qian, X., Yin, T., Li, T., Kang, C., Guo, R., Sun, B., et al. (2012). High Levels of Inflammation and Insulin Resistance in Obstructive Sleep Apnea Patients with Hypertension. Inflammation. 35(4), 1507-1511.

Sacchetti, Lisandro, M., Mangiardi & Priscilla. (2012). Otolaryngology research advances : Obstructive sleep apnea: Causes, treatment and health implications. USA: Nova Biomedical

Sharma, S. K., Vasudev, C., Sinha, S., Banga, A., Pandey, R. M., & Handa, K. K. (2006). Validation of the modified Berlin questionnaire to identify patients at risk for the obstructive sleep apnoea syndrome. Indian Journal of Medical Research, 124(3), 281-290

Soylu, A. C., Levent, E., Sariman, N., Yurtlu, S., Alparslan, S., & Saygi, A. (2012). Obstructive sleep apnea syndrome and anthropometric obesity indexes. Sleep and Breathing, 16(4), 1151-8.

Walia, H. K., Li, H., Rueschman, M., Bhatt, D. L., Patel, S. R., Quan, S. F., . . . Mehra, R. (2014). Association of severe obstructive sleep apnea and elevated blood pressure despite antihypertensive medication use. Journal of Clinical Sleep Medicine, 10(8), 835-843.




How to Cite

Astridivia, M., & Kuntarti, . (2017). ASSOCIATION OF OBSTRUCTIVE SLEEP APNEA AND BLOOD PRESSURE ON HYPERTENSIVE PATIENT IN DEPOK INDONESIA. LIFE: International Journal of Health and Life-Sciences, 3(2), 106–117.