A REALITY IN A DEVELOPING COUNTRY- BENIN: DIAGNOSIS OF CANCER WITH THE ACTIVATION OF AUTOMATED IMMUNOHISTOCHEMISTRY

Authors

  • Dr. Tiziano Zanin E.O. Ospedali Galliera, 16128 Genova, Italy

DOI:

https://doi.org/10.20319/lijhls.2019.43.128137

Keywords:

Telepathology, Histopathology Laboratory, Immunohistochemistry

Abstract

Background: In the Benin-West state of Africa, cancer is one of the most frequent causes of death. For this reason from September 2015 at Saint John of God Hospital in Tanguieta – Benin – a Histopathology Laboratoy is active with the aim to make diagnosis and address towards adequate therapeutic programs patients affected from cancer and other diseases. The Laboratory has been equipped with a tele pathology system (Cross SS, Dennis T, Start RD. 2002 and Della Mea V. & Beltrami CA. 2000) and from 2018 with an Automatic System for Immunochemistry.Objectives, methods and outcomes: In the last 20 years, in collaboration with the association APOF (Pathologists across the border), diagnostic laboratories have been developed in various African countries: Tanzania - Uganda - Djibouti, etc. Immunohistochemistry has been introduced in these laboratories to formulate a correct and complete diagnosis.In Benin we had a technological breakthrough by introducing an automated immunohistochemistry system. The funds were obtained from the FAI (International Assistance Foundation) of Lugano (Switzerland) and from the UTA – Onlus.The use of validated protocols, the contribution of international experts through telepathology, the training of technical personnel on site, allowed the formulation of correct diagnoses.Conclusion: The development of complete histopathological diagnostic services of automated ICHs, such as that of Benin, is of fundamental importance for the fight against cancer in developing countries. Cancer is fought with research but also with a correct diagnosis.

References

Afework A. Beynon MD. Bustamante F. Cho S. Demarzo A. Ferreira R. Miller R. Silberman M. Saltz J. Sussman A. Tsang H. Digital dynamic telepathology--the Virtual Microscope. Proceedings / AMIA Annual Symposium. :912-6, 1998.

Cross SS, Dennis T, Start RD. Telepathology: current status and future prospects in diagnostic histopathology. Histopathology 2002; 41:91-109.

Della Mea V, Beltrami CA. Current experiences with internet telepathology and possible evolution in the next generation of Internet services. Anal Cell Pathol 2000; 21:127-34.

Giorno R. A comparison of two immunoperoxidase staining methods based on the avidin-biotin interaction. Diagn Immunol. 1984;2(3):161-6.

Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61(2):69–90. http://dx.doi.org/10.3322/caac.20107

Key M. Education guide: Immunohistochemical Staining Methods

http://www.dako.com:Dako; 2009 [5th:[Chapter 9: Immunohistochemistry Staining Methods

Krupinski E, Weinstein RS, Bloom KJ, Rozek LS. Progress in telepathology: System implementation and testing. Advances in Path Lab Med 1993; 6:63-87.

Krupinski EA. Virtual slide telepathology workstation-of-the-future: lessons learned from teleradiology. Semin Diagn Pathol 2009; 26:194-205.

Leung ST, Kaplan KJ. Medicolegal aspects of telepathology. Hum Pathol 2009; 40:1137-1142.

O'Malley DP. Practical applications of telepathology using morphology-based anatomic pathology. Arch Pathol Lab Med 2008; 132:743-4.

Shyyan R, Masood S, Badwe RA, Errico KM, Liberman L, Ozmen V, et al. Breast cancer in limited-resource countries: diagnosis and pathology. Breast J. 2006;12(s1):S27–S37. http://dx.doi.org/10.1111/j.1075-122X.2006.00201.x

Weinstein RS, Descour MR, Liang C, et al. Telepathology overview: from concept to implementation. Hum Pathol 2001; 32:1283-99.

Weinstein RS, Graham AM, Richter LC, Barker GP, Krupinski EA, Lopez AM, Erps KA, Yagi Y, Gilbertson JR, Bhattacharyya AK. Overview of telepathology, virtual microscopy and whole slide imagining: Prospects for the future. Hum Pathol, 2009; 40: 1057-10

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Published

2019-02-18

How to Cite

Zanin, T. (2019). A REALITY IN A DEVELOPING COUNTRY- BENIN: DIAGNOSIS OF CANCER WITH THE ACTIVATION OF AUTOMATED IMMUNOHISTOCHEMISTRY. LIFE: International Journal of Health and Life-Sciences, 4(3), 128–137. https://doi.org/10.20319/lijhls.2019.43.128137